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Metabolism: Modafinil undergoes hepatic metabolism by means of multiple pathways, like CYP3A4. eighty% of the dose is recovered from the urine in the shape of metabolites.itraconazole will enhance the level or impact of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.Though scientific studies haven't proven any
The bioavailability of modafinil is nearly similar to that of a liquid suspension. The entire oral bioavailability was not found out due to water insolubility (35 periods These acquired therapeutically9.Nuvigil is produced inside a greater range of dosing increments as compared to Provigil. It is often administered in a starting dose of a hundred a
modafinil will reduce the extent or impact of mavacamten by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.modafinil will decrease the level or influence of fruquintinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. If coadministration with reasonable CYP3A4 inducers is unavo